NEWS

New paper published on Cell Death and Differentiation

2025 Mar 3. doi: 10.1038/s41418-025-01470-2

This study identifies KDM3A as a key regulator of postnatal hippocampal neurogenesis, through dual regulation of the Wnt/β-catenin signaling pathway. The findings highlight KDM3A's potential as a therapeutic target, as its loss impairs neurogenesis and brain injury repair, while the geroprotective molecule quercetin enhances KDM3A expression to promote neurogenesis.